H2 antihistamine (e.g., famotidine, cimetidine) H1 antihistamine (e.g., diphenhydramine, cetirizine)† If feasible, include at locations (not required)Įpinephrine (e.g., prefilled syringe, autoinjector)* Medications and supplies for assessing and managing anaphylaxis Should be available at all locations The following emergency equipment should be immediately available for the assessment and management of anaphylaxis. Vaccination locations that anticipate vaccinating large numbers of people (e.g., mass vaccination clinics) should plan adequate staffing and supplies (including epinephrine) for the assessment and potential management of anaphylaxis. Healthcare personnel who are trained and qualified to recognize the signs and symptoms of anaphylaxis, as well as administer intramuscular epinephrine, should be available at the vaccination location at all times. Personnel, medications, and supplies for assessing and managing anaphylaxis A COVID-19 prevaccination questionnaire is available to assist with screening. Patients should be screened prior to receipt of each vaccine dose, and those with a contraindication should not be vaccinated. Detailed information on CDC recommendations for vaccination, including contraindications and precautions to vaccination, can be found in the Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States. These interim considerations provide recommendations on assessment and potential management of anaphylaxis following COVID-19 vaccination.
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